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University of California in Riverside (UCR) investigators say they may have discovered a new target for drugs in treating a neurodegenerative form of dementia called Alzheimer’s Disease. The molecule they discovered could also be targeted in the fight against other neurological disorders.
During the study, th... |
13 February 2012 06:00 GMT |
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A group of researchers at the University of Utah proposes a new explanation for why vertebrates including humans and rats still hold on to numerous genetic variants that make them susceptible for being infected by foreign pathogens, or triggering autoimmune diseases.
The genetic variants the team focused its effort... |
7 February 2012 03:00 GMT |
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A collaboration of researchers at the University of Texas Medical Branch say that conglomerations of between 2 and 4 tau proteins (oligomers) are the most damaging molecular contracts to the human brain. This proteins has been linked to the development of Alzheimer's disease in previous studies.
What researcher... |
4 February 2012 06:50 GMT |
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A new class of proteins responsible for controlling the way in which the body responds to hypoxic situations (in which insufficient amounts of oxygen are available to conduct regular processes) has just been discovered by a collaboration of investigators in the United Kingdom.
Experts at the University of Nottingha... |
31 January 2012 04:13 GMT |
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A group of experts at the U.S. Department of Energy's (DOE) Lawrence Berkeley National Laboratory (Berkeley Lab) were recently able to produce the first 3D image of an individual protein ever obtained.
This was made possible when scientists at the lab's Molecular Foundry pushed their Zeiss Libra 120 Cryo-T... |
25 January 2012 16:31 GMT |
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Reading, solving math problems, doing puzzles and many other activities that stimulate cognitive processes help prevent the development of a form of neurodegenerative dementia called Alzheimer's disease, researchers at the University of California in Berkeley (UCB) argue in a new study.
Making a lifetime habit... |
24 January 2012 09:27 GMT |
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For years, oncologists have been trying to figure out how glioblastoma – an extremely aggressive and deadly form of brain cancer – develops in the human body. In a new research, scientists were finally able to discover a mechanism that previous investigations never even hinted at.
One of the main direct... |
18 January 2012 03:14 GMT |
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Given that Parkinson's disease is largely triggered by the release of a particular protein in the human brain, discovering the condition when it sets on implies being able to prevent this molecule from building up in the brain. This is precisely what a team of researchers recently managed to accomplish.
But, wh... |
17 January 2012 04:00 GMT |
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University of California in Los Angeles (UCLA) scientists determined that teens who exhibit a deficiency of iron tend to be at higher risk of suffering conditions affecting the brain later on in life.
The risk mostly addresses forms of dementia such as Alzheimer’s disease. This correlation has been hinted at ... |
16 January 2012 05:21 GMT |
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Genetically-modified silkworms have been a goal for breeders for years. The most important goal that researchers tried for was to insert spider silk proteins into the silkworms, so that the latter would have been able to produce stronger silk. After years of failure, that objective was finally reached.
Successful c... |
4 January 2012 09:55 GMT |
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In a study conducted on a species of grasshopper called the Desert Locust, researchers finally managed to identify what makes the creatures move from a solitary, secluded phase to a gregarious one. Apparently, it all comes down to the actions of a single molecule.
The research team explains that the molecule they i... |
20 December 2011 06:15 GMT |
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A new study by researchers at the Pasteur Institute, in Paris, shows that cellular proteins called septins play an important role in helping the human body deal with the consequences of bacterial infections. The molecules are known to be involved in a host of cellular processes, such as for example providing structu... |
6 December 2011 06:36 GMT |
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In a paper published in the December 5 issue of the top scientific journal Nature Cell Biology, a team of experts presents a new Achilles heel for cancer cells, which they say can be exploited for novel therapies against different forms of cancer.
The group noticed during investigations that these cells are in the ... |
5 December 2011 09:28 GMT |
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A group of scientists led by expert Daniele Piomelli, at the University of California in Irvine, announces the development of a new method for boosting the effects of marijuana-like compounds that occur naturally in the brain. Their achievement may lead to the creation of new classes of drugs.
The target molecule is... |
28 November 2011 03:05 GMT |
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Neuroscientists at the Massachusetts Institute of Technology (MIT), in Cambridge, say that they were recently able to identify the single genetic mutations that are responsible for the development of several conditions in the autism spectrum (ASD).
The finding is bittersweet in a way, since scientists addressed cond... |
24 November 2011 08:59 GMT |
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Schizophrenia and autism spectrum disorders (ASD), among other mental disorders, may be partially caused by insufficient concentrations of a protein called densin-180 in the brain. The new results were derived from studies carried out on lab mice. While most mental diseases humans can develop are unique to our spec... |
23 November 2011 06:22 GMT |
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In a groundbreaking new study, a team of Australian investigators was able to develop a new method of addressing spinal cord injuries in animals. Their progress, if translatable to humans, could lead to the development of treatments that would cure thousands of people suffering from paralysis.
The condition has mult... |
16 November 2011 04:42 GMT |
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A group of investigators at the Brown University reveal in the November 6 issue of the top journal Nature Chemical Biology the exact structure of a critical enzyme complex. Knowing this molecular structure could lead to the development of new drugs against a wide range of conditions.
Some of these conditions includ... |
7 November 2011 03:46 GMT |
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In a study funded by the Canadian Cancer Society Research Institute and the Canadian Institutes of Health Research, researchers discovered that the protein S100A10 is critical for the growth of tumors during the last phase of cancer.
Metastatic growth is a term referring to the development of tumors at many locatio... |
1 November 2011 05:30 GMT |
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In a paper published in last week's issue of the top scientific journal Nature Chemical Biology, a group of scientists from the University of Bristol, in the United Kingdom, announces the development of a new protein. The type of architecture this molecule contains does not exist in nature.
The artificial prot... |
31 October 2011 04:04 GMT |
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Scientists have known for a long time that pilots using a flight simulator exhibit a downward curve when it comes to performances the older they get. However, a new study uncovered that a specific variant of the BDNF gene causes performances to decrease faster than normal.
The gene, whose full name is the brain-der... |
26 October 2011 06:54 GMT |
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A group of investigators at the Lehigh University is hard at work for developing a new type of nanodevice that would be capable of addressing the effects of cardiovascular system conditions such as thrombosis, atherosclerosis and stroke.
Lead researcher Xiaohui Zhang is hoping to achieve this by combining concepts ... |
26 October 2011 04:57 GMT |
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A collaboration of researchers coordinated by investigators at the Scripps Research Institute (SRI) recently uncovered a new approach to addressing brain inflammation. Their method does not cause the type of side-effects that drugs such as ibuprofen do.
The approach relies on blocking the action of a single enzyme,... |
21 October 2011 06:41 GMT |
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A collaboration of scientists from the US Department of Energy's (DOE) Lawrence Berkeley National Laboratory (Berkeley Lab) announces that it has observed for the first time the mechanisms that slim sheets of protein-like structures use in order to self-assemble. By emulating and replicating this process, it may... |
18 October 2011 06:53 GMT |
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A group of researchers from the Loyola University Chicago (LUC) announces the development of a new cure for SCA1, a fatal, progressive disorder affecting the central nervous system. The team reports that the treatment shows great promise. Spinocerebellar ataxia (SCA) in fact represents a wider array of disorders, in ... |
17 October 2011 04:23 GMT |
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The intricate interplay between various types of neurons that leads to the development of schizophrenia is currently the target of three separate labs at the University of Pennsylvania Perelman School of Medicine. In their latest report, the investigators say that sounds affect how the condition is triggeredIn other ... |
17 October 2011 02:26 GMT |
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A vital biomolecule has been sequenced for the first time at the Rensselaer Polytechnic Institute (RPI), by a team of experts coordinated by researcher Robert Linhardt. He is the Ann and John H. Broadbent Jr. ’59 Senior Constellation Professor of Biocatalysis and Metabolic Engineering at the institute.
Biku... |
11 October 2011 10:39 GMT |
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An international collaboration of scientists has recently developed a new approach to treating diseases such as atherosclerosis and cancer. Their technique relies on the use of short RNA snippets, which can be used to shut down a very specific gene on immune cells, therefore reducing inflammation.
Scientists at t... |
10 October 2011 03:41 GMT |
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According to the conclusions of a new study on the way Alzheimer's disease damages the human brain, it would appear that the condition triggers an infectious process of sorts, which researchers found to be eerily similar to the one employed by mad cow disease (MCD).
Scientifically known as bovine spongiform e... |
6 October 2011 06:58 GMT |
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Scientists with the University of Leicester, in the United Kingdom, say they've made an important discovery while analyzing the code on which the human brain operates – a new, key actor involved in determining how the cortex deals with, and mitigates for, daily stress. In modern societies, stress is ever-p... |
4 October 2011 11:13 GMT |
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Investigators at the University of Cambridge, in the United Kingdom, announce the creation of a new drug that can be used to treat one of the most common forms of blood cancer, mixed-lineage leukemia (MLL). The condition oftentimes affects babies.
In a paper the team published in the October 2 issue of the top sc... |
3 October 2011 04:56 GMT |
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Between 30 and 50 percent of all modern-day drugs are destined to affect the way a class of molecules called G protein-coupled receptors (GPRC) works. A research group featuring researchers from around the world recently managed to create a precise model of how these receptors are organized.
The study, which also ... |
30 September 2011 08:46 GMT |
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At this time, many drugs against obesity and diabetes are available on the market, but most of them have their actions disrupted by an enzyme called PTP1B. Researchers in the United States now say that they can use this molecule as a target for a new type of treatment.
The team – which is based at the Cold S... |
30 September 2011 05:44 GMT |
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Georgia Health Sciences University graduate student Scott Webster says that targeting the amyloid protein and its pathways could lead to the development of a new type of vaccine against Alzheimer's.
The disease, a neurodegenerative form of dementia, is incurable and fatal over time. It first acts by reducing ... |
27 September 2011 02:52 GMT |
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A group of experts at the Michigan State University (MSU) announce the development of a new vaccine against malaria, one that takes an innovative route towards destroying the parasite that produces the disease.
According to the investigators, the vaccine relies on the use of a disabled cold virus, which is augmen... |
26 September 2011 09:46 GMT |
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For many years, researchers have tried to determine the structure of a retrovirus enzyme, a special protein that is employed by a class of viruses including HIV. Now, players of the online game Foldit managed to solve this complex structures where many scientists failed using more advanced methods.
Foldit is an o... |
20 September 2011 18:01 GMT |
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For many years, experts have tried to find the cause of Parkinson's disease, but more in-depth studies have revealed that there is no single trigger for the condition. Rather, it is influenced by a complex interplay of genes and genetic mutations that each plays a part in underlying this form of dementia. One of... |
12 September 2011 11:01 GMT |
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In a significant advancements that could lead to improvements in tissue engineering, cosmetics and reconstructive surgery, experts at the Rice University managed to develop a new method for producing the synthetic form of a very common protein in the human body, collagen.
This molecule is tremendously important b... |
9 September 2011 14:01 GMT |
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A group of researchers at the University of Leeds, in the United Kingdom, says that their latest study provides more insight into the genetic roots of inherited eye disorders affecting young children.
The study used next-generation DNA sequencing methods to get the job done. Some of the conditions that were inves... |
9 September 2011 05:33 GMT |
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During a recent investigation conducted on unsuspecting lab mice, researchers learned that turning off just two genes in the tiny rodents led to a massive decrease in the amount of physical activity they put forth. The animals' ability to run was the most severely impeded, the team reports.
Given the similar... |
6 September 2011 05:44 GMT |
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Some of the most common, naturally-occurring biominerals, such as for example seashells, will soon be reproduced thanks to a new technique developed by investigators at the University of Leeds.
Researchers here were recently able to recreate synthetic crystals whose structures and properties closely mimic those o... |
5 September 2011 08:45 GMT |
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Ever since the first lifeforms developed on our planet, their basic components were founded on a specific group of 20 molecules in a group called amino-acids. A particular set of combinations made life possible here, but it could be that different amino-acids did the same on other worlds, experts say.The reason why t... |
18 August 2011 09:14 GMT |
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A new blood test developed by researchers at the University of Medicine and Dentistry of New Jersey (UMDNJ) could be used to detect symptoms produced by Alzheimer’s disease a lot faster than ever before. The approach can set the foundation for rapid, early diagnostics methods.Alzheimer’s is a neurodegener... |
5 August 2011 10:11 GMT |
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A collaboration of six universities and research centers has taken an unorthodox approach to searching for drugs that may combat a fierce type of blood cancer, called acute myeloid leukemia. The work has already discovered a potent drug candidate.The research team, which also included investigators from the Cold Spri... |
4 August 2011 03:10 GMT |
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Researchers announce the creation of the first systematic interactome, a map of all the interactions that occur between proteins in a plant species. The mustard plant Arabidopsis thaliana – commonly used in research – was selected for this research. The plant contains more than 27,000 proteins, and resear... |
29 July 2011 08:09 GMT |
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In a new study, experts decided to use the evolutionary “lens” in order to understand the complex process of blood clotting. Gaining new insight into what happens at this time could help scientists develop new cures for bleeding disorders.Whenever people cut themselves, even if the wound is minor, the bod... |
21 July 2011 05:59 GMT |
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A recent set of studies reveals the methods some bacteria employ in order to destroy competition. Many colonies fight to keep other invading cells at bay, and researchers have just obtained a deep insight into one of these elaborate strategies. According to investigators, one of the technique certain species of micro... |
21 July 2011 03:47 GMT |
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Researchers found a direct correlation between getting sufficient amounts of vitamin D and a reduced risk of developing Alzheimer's disease, a neurodegenerative disorder that is affecting more and more seniors across the world.In the new investigation, investigators tested the protective properties of vitamin D ... |
11 July 2011 10:12 GMT |
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An international group of researchers is currently working towards gaining a deeper understanding of the factors that lead to inherited intellectual disability. In order to find out more about this, they are using genetically-altered fruit flies as proxies. In an investigation conducted on several Iranian families, g... |
5 July 2011 03:37 GMT |
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An enzyme that plays an important role in regulating the development of a highly-aggressive form of cancer has just been identified, potentially providing researchers with a new avenue of research for creating a new series of treatments against the condition.The enzyme PTPN23 was discovered by experts at the Cold Spr... |
1 July 2011 07:42 GMT |
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