How the Herpes Virus Defeats Cellular 'Guards'

Researchers at the La Jolla, California-based Salk Institute for Biological Studies have recently determined one of the key mechanisms the herpes simplex virus (HSV) uses to keep cells unaware of the fact that it has infected them. This “covert” approach to infecting the human bod... [ read more >> ]

When cells with DNA damage are infected with the HSV-1 virus (virus shown in red), the viral ICP0 protein prevents the DNA repair proteins (green) from accumulating at sites of DNA damage

Image comment: When cells with DNA damage are infected with the HSV-1 virus (virus shown in red), the viral ICP0 protein prevents the DNA repair proteins (green) from accumulating at sites of DNA damage
Image credits: Courtesy of Dr. Caroline Lilley / Salk Institute for Biological Studies

When cells with DNA damage are infected with the HSV-1 virus (virus shown in red), the viral ICP0 protein prevents the DNA repair proteins (green) from accumulating at sites of DNA damage