Chili Peppers Against the Pain, without Numbness

Chili peppers can send you to hell and maybe back (we don't know for sure…), but even so, what causes sufferance can also bring relief. Capsaicin, the 'hell-inducing' chemical from the jalapeños and habañeros is already a main ingredient in a balm for stiff joints and arthritis... [ read more >> ]



Double-teaming pain.Capsaicin (red) opens up pain neurons' TRPV-1 channels (blue) so that QX-314 (yellow) can enter and block sodium channels (green).

Image comment: Double-teaming pain.Capsaicin (red) opens up pain neurons' TRPV-1 channels (blue) so that QX-314 (yellow) can enter and block sodium channels (green).
Image credits: McCleskey

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Double-teaming pain.Capsaicin (red) opens up pain neurons' TRPV-1 channels (blue) so that QX-314 (yellow) can enter and block sodium channels (green).