NEWS CATEGORIES:



NEWS ARCHIVE >>
SOFTPEDIA REVIEWS >>
MEET THE EDITORS >>
Home / News / Science / Health

Health


Breast Cancer's Lethal Triad

Linked to triple negative tumors

By Stefan Anitei, Science Editor

26th of March 2007, 13:40 GMT

Adjust text size:



Enlarge picture
A peer-reviewed study of the American Cancer Society revealed the deadly triad for female breast cancer: African American or Hispanic, younger than
40 years, and lower socioeconomic status (SES).

This triad of the breast cancers and tumors does not respond to any of three significant tumor markers, are aggressive, deadly cancers that affect young, poor minority women.

The triple negative tumors were also linked to later diagnosis and shorter survival. Tumor and tissue markers offer crucial information about the disease type, essential for prognosis and to selecting the appropriate adjuvant therapy.

In the case of breast cancer, the most important markers are estrogen receptor (ER), human epidermal growth factor receptor 2 (HER2), and progesterone receptor (PR). Roughly 15 % of breast cancers do not signal to any of these markers and are generally assessed as basal-like subtypes.

These determines poor prognosis and survival, therapy failure, and are often detected in African American women, but very little is understood about other factors linked to this condition.

A team led by Katrina Bauer from the Public Health Institute in Sacramento, California made a comparison of the demographic, clinical and survival patterns of 6,370 women diagnosed with triple negative breast cancers with 44,704 women with other breast cancer types. They detected race and age, in particular, but also socioeconomic factors as the most risky for the triple negative breast cancer.

Compared to Caucasians, African American women presented the highest risk followed by Hispanic women. Also women under 40 years old were more prone than women over 60 years old. Lower SES was also found to be an aggravating factor.

The triple negative tumors were found to be more aggressive, diagnosed much later (in advanced stages) and linked to shorter survival, regardless of when they were found.

Only 14 % of the African American women were found to survive the next five years after diagnosis.

Bauer's team concluded that "age less than 40 years, being non-Hispanic black and, to a lesser extent, being Hispanic, are clearly the most powerful risk factors for this poor prognosis subtype of breast cancer."

TAGS:

breast | cancer | marker | diagnosis
Read by 2,846 user(s) | Add comment | Link to this article TWEET THIS


Article rating:
Good (3.5/5) 6 vote(s)    

Subscribe to news | Print article | Send to friend

© Copyright 2001-2009 Softpedia
Contact:

 

 

SEARCH THE NEWS ARCHIVE :




Today's News
| Yesterday's News | News Archive


MORE RELATED ARTICLES:


Black Men More Likely to Die of Breast Cancer than White Men

Which Are the Risks of Breast Implants?

Variations In Female Sex Hormone Formula Increase the Risk of Breast Cancer

Breast Implant Increases Self-Esteem, Sex Drive and Satisfaction

Black Women Develop Earlier Breast Cancer and Are More Prone of Dying from It

Fat from the Belly to Boost Natural Looking Boobs

Men That Produce Milk

Silicone Breast Implants Cause Immunity Problems, Even Cancer

Fat/Obese Girls Are Given to Early Sex

Why Do Women Have Breasts?

User opinions:


Comment #1 by: leslielandberg on 10 Jun 2008, 00:46 GMT reply to this comment

Environmental factors coinciding with lifestyle and cultural behaviors are going to be found, eventually, to the the cause. I live in oakland, and the people whom I know who come from the lower class and are ethnic are many. Almost without exception they eat a lot of fast food, drink a lot of soda, many of them smoke or drink. Many of them eat to excess regularly and don't eat nearly enough fresh fruits and vegetables. Many of them come from economically disadvantaged families forced to live in less-than-ideal neighborhoods plauged by soil and air pollution and high levels of stress caused by neighborhood violence, the untimely deaths of loved-ones and broken homes. The hormone cortisol is a killer. I am writing this in hopes that people of color will click on this article and view my opinion - it may save their lives. Back to it: Cortisol is a hormone linked with obesity, heart disease and cancer. The levels of severe (morbid) obesity in the at-risk community is off the chart - particularly for females, where it is estimated that one in three are severely overweight. This is clearly a co-factor. Many, many of the Hispanic and black kids these days are shockingly obese. This plays havoc with the endocrine system and sets the stage for many serious illnesses - including breast cancer. In addition to sodas and junk-food, even if the people from this class strive for a more balanced diet including fresh fruits and vegetables, they will more than likely be consuming "conventionally-grown" produce, not organically grown, due to it's prohibitive cost and the fact that the better grocery stores are likely to be outside of their neighborhoods. The reason this is a grave concern is that conventional food is dangerous to eat due to massive petrochemical contamination and GMO modification. All conventional foods are grown with massive amounts of fertilizer and generous applications of weed-killer and insecticides - all brought to you curtesy of those great guys at Shell and Monsanto and all of them made with petrochemicals i.e. crude oil. The residues get into the flesh and skin of the fruits and vegetables and then into us. It is not water-soluble and thus collects in our tissues over time giving us cancer - primarily in women breast and ovary cancers and in men it is testicular and prostate cancer. In men it will also cause gynocomastia. Male breast cancer has been steeply on the rise! The reason for it is that the body detects the chemicals and they mimic estrogens. Too many estrogens in the body (esp. fake ones, call zenoestrogens "strange" estrogens, literally) will cause men to grow breasts and become infertile and cause women to grow cancers and tumors. If you think this is bad enough, well wait: there's a lot more! If you eat meat or eggs or cheese you are in for a whammy: there is nearly 15 times more concentrated deadly petrochemicals in those products. And to make matters worse...even if you had the extra $$$ to pony up for that nice "organic" steak at the Walmart, well, guess what? It's not really organic at all - it's "feed-lot" meat - ordinary, conventionally-grown steak. So it is hard to find the real thing...the cows eat the grain which is grown conventionally and it all stores up in their tissue and you eat the result: concentrated toxins. Also, many of my friends from the black and latino community really like their cosmetics! You girls have to have your nails done and slather your bodies with all kinds of make-up and bath junk. it's great to be well-groomed, but all of these products have high levels of toxins in them. Bottom line, get educated. Take a trip to your local health-food store and ask some hard questions. Do some internet searching and share the information with all your girlfriends. Oh, one last thing: don't drink tap water, okay??? It's laced with all sorts of nasty chemicals that are super toxic over time, so don't do all those long hot showers and hot bath-tub soaks: you're getting massive doses of the same xenoestrogens as in the meat! This time it is from two main sources: chloromines and birth-control pills. That's right: when you pee your hormone-laden urine goes right back into the drinking water system and it builds up worse and worse every year that goes by. These both produce the xenoestrogenic effect, making you sick. There is so much more I could tell you, but here's the bottom line: it takes weeks and months to fully detox from this cancerous contamination. Start now: eat locally produced organic fresh fruits and vegetables, drink Crystal Geyser water (and don't let it sit in the car - I almost forgot: get rid of the microwave and all your plastic storage and cooking utensils immediately - the plastics in them are massive sources of xenoestrogens in your bodies.) Go vegan or eat certified organic chicken and meat from small local farms (not Safeway or Walmart brand, honey!), drink a lot of water all the time. Don't drink any more soda...don't eat any more junk food. Don't ever go to a fast food restaurant. YES I'M SAYING CHANGE YOUR WHOLE FRIGGING LIFESTYLE! YES IT'S TOTALLY INCONVENIENT. SO IS DYING OF CANCER...

Share your opinion:

Your Name:
Your Email Address:
(will not be used for commercial purposes)
Solve this to prove you're not a bot: =
Your review/opinion:

 




Windows tabGames tabDrivers tabMac tabLinux tabScripts tabMobile tabHandheld tabGadgets tabNews tab

SUBMIT PROGRAM   |   ADVERTISE   |   GET HELP   |   SEND US FEEDBACK   |   RSS FEEDS   |   ENTER NEWS SITE   |   ENGLISH BOARD   |   ROMANIAN FORUM