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June 27th, 2007, 18:11 GMT · By Stefan Anitei

The Amazing Cases of People with Natural Immunity against HIV

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HIV has been rampant in Africa from the early '80s. More than 20 years ago, the disease appeared in Nairobi (Kenya), infecting 90% of the city's lower-class prostitutes; but some women practicing this "business" for over 13 years have not developed AIDS. Not having AIDS symptoms is not so shocking, since HIV can stay dormant in the body
for many years before it starts to kill.

The surprise is that HIV cannot be detected in these women at all; it apparently cannot stick itself in their cells.

There are also cases of people in other high-risk groups, like homosexuals and spouses of infected hemophiliacs, that do not catch the infection. But these prostitutes, so frequently exposed to the HIV for so long come with the strongest proof yet that people can display a natural immunity to HIV, that removes the danger of AIDS. If the precise reason of that protection can be detected, the humankind could finally get an anti-HIV vaccine.

A mixed Kenyan-Canadian team has monitored a group of 25 Nairobi prostitutes monthly for at least six years, in an intensive survey. Each of the them has had sex with hundreds, perhaps thousands, of HIV-positive clients. And they don't use condoms more often than other prostitutes that got infected with HIV and developed AIDS.

Moreover, they have experienced other sexually transmitted infections, like syphilis and gonorrhea. Lead researcher Dr. Francis Plummer of the University of Manitoba suspects the reason may be found in some proteins called human leukocyte group A antigens. They coat the cells' surface, helping detect foreign invaders like viruses. Preliminary results point to the fact that the HIV-free women have HLAs significantly different from the common types found in people that develop AIDS, but the precise way in which these mutated HLAs can reject HIV infection is still unknown.
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AIDS

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READER COMMENTS:


Comment #1 by: 1222gggg on 26 Sep 2010, 20:07 UTC reply to this comment

My girlfriend was Hiv for the past 4 years, she knew about, we started dating 2 years ago, at first i was using condoms later she deceived me not to use condoms that was after 4 months.

5 months ago Unfortunately she fell sick i never wanted to see the doctor, as the sickness get worst she couldn't stand it so i took her to the clinic and they found out she is Hiv , i was scared that i couldn't go for test later after a month i decide to get tested i found out i was negative, how could it be i still dont believe i am negative because i made so much research about HIV and it was stated that most Africans dont have CCR5 in there blood. its mostly found among 10-15% of Europeans, i am 100% full african. IF you come across this please give me answers

Comment #1.1 by: surfergirl on 23 Jun 2011, 08:29 GMT

There are a couple of other explanations for natural immunity such as an increase in a certain protein called human leukocyte or a defect on the CD4 cell that doesn't allow the virus to replicate so it can't survive in the body. Other possible explanations are that the hiv virus is not necessarily spread every time you have sex, and while definitely not impossible, it is slightly more difficult for men to contract hiv from women just through intercourse than it is for women to contract it from me. Another possibility is sheer luck.


Comment #2 by: davidNPR on 28 Nov 2010, 03:07 UTC reply to this comment

I lived in san framcisco before during and at the height of the aids epidemic. I have been with a large number of hiv infected men, yet never contracted it myself. One suggestion is that I have a natural immunity to it. If so, I would love to offer my blood for research. Can anyone tell me how I can do that? thanx!

Comment #2.1 by: Simon on 15 Jul 2011, 13:25 GMT

You should google the nairobi-candian team who are researching this. You never know you may have the cure to one of the worlds cruelest infections - that would be Godly!


Comment #3 by: tjbeeman on 31 Dec 2011, 05:57 UTC reply to this comment

It's a goo development. More intrensive research would help reveal the precise way in which the mutated HLAs can reject HIV infection, and that will help to save the world from the dreaded virus. More power to your elbow.

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