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Home > News > Science > Microbiology/Genetics

June 13th, 2007, 20:31 GMT · By Stefan Anitei

Top 11 Most Common Human Mutations

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You share about 49.99 % of your genes with the guy next door. With her also the same amount. But there may be some mutations you have produced. Or received from them.

And usually mutations are rather nasty.

1. Baldness is more common in men, as testosterone sensitive form is the most common.

But geneticists still do not know what's going on there. Genes are involved, and baldness is due to mutations in several genes from one or both parents.

2. Chinese lack, in one of the rare cases of this type, a beneficial mutation that enables others to eat milk and dairy products. Chinese distaste for milk was thought to be a cultural one, until the 1960s lactose intolerance was found in many populations in Eastern and Southeastern Asian, but also some Africans. Within the past 10,000 years, the beneficial mutation spread only where dairy farming was the norm.

3. Pimples, too, are linked to a family history. If your parents experienced bad pimples, you are more likely to suffer of severe acne
too.

4. Another beneficial (or bad, depending on the case) aspect is high fertility in women. Identical twins are random events, but fraternal twins emerge in families again and again.

A gene is involved in multiple eggs released during ovulation (hyperovulation).

Men carrying the gene will not necessarily father twins, as this depends on the woman, but their daughters can give birth to twins when they receive the gene. That's why twins can skip generations.

5. Heart disease, diabetes, stroke or high blood pressure come in family. If parents experienced it, children present the likelihood of developing them too.

6. Studies bind obesity to a heavy set of genes. These genes were beneficial to our ancestors, as they could store "reserves" during scarcity periods. But today, there are no shortage periods. Also, many of today's obesity cases are linked to eating too much "unhealthy" food.

7. The male "aggressive behaviors" are more likely to be encoded in genes than non-aggressive antisocial behaviors like stealing. But genes can be behind the stealing behavior in women.

8. Ten million men in the U.S. are color blind (they cannot differentiate red from green) but less than 600,000 American women have the same disability. That's because this mutation is located on the X-chromosome.

Men only have one X-chromosome, so that one is enough to induce the condition, but women have two X chromosomes, and they require the mutation in double set to experience the condition.

9. Increasing evidence links breast cancers to particular genes. Those with mutation tend to develop cancer earlier and in both breasts. The same mutations increase the risk of developing prostate, breast, pancreas and other cancers in men.

10.Half of the alcoholism risk seems to be hereditary, but the environment also plays its role. There are several genes involved, working differently from one individual to another.

11.The chin dimple is caused by an incomplete fusion of the right and left sides of the jaw when encountering on the chin area. This menton symphysis, if incomplete, appears as a dimple: it is determined by a dominant gene, and its absence by a recessive gene.
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READER COMMENTS:


Comment #1 by: Ruby on 01 Oct 2008, 08:44 UTC reply to this comment

Are pimples really genetic??

Comment #1.1 by: Albert on 17 May 2012, 09:58 GMT

yes sir :)


Comment #2 by: Gaby on 21 May 2009, 00:06 UTC reply to this comment

1. What is pimples?
2. Didn't you say "dimples"
3. If your intention was saying dimples, yes they are genetic.
4. Are there any other benefitful mutations?
5. Very good web page, it helped me with my homework!

Comment #2.1 by: nick246824 on 22 Nov 2010, 21:29 GMT

He wasnt talking about number 11 on the list, he was talking about # 3 u tried to be smarter lol


Comment #3 by: Virgil H. Soule on 02 Sep 2009, 23:35 UTC reply to this comment

Is it really mutations (spontaneous genetic changes) that produce these things or are they produced by aberrant genes or alleles? If mutations are accidental why do some occur over and over again in the human population? Down's Syndrome, for example. I saw a show on TV about Primordial Dwarfism. This one couple's first child was diagnosed with the syndrome. Experts in genetics assured them that it was a one-in-a-million accident and would likely never happen again. So, they went ahead and had a second child. Lo and behold, the second child was diagnosed with the same thing. How is this explained?

Comment #3.1 by: i like your arguemnt on 19 Sep 2010, 09:28 GMT

i think your question here is valid and deserve some searching here
i doubt that these are mutation , i think these syndromes of related diseases that are related to genetics is caused by recessive genes rather than mutations

Comment #3.2 by: nick246824 on 22 Nov 2010, 21:32 GMT

it is a type of mutation. Remember mutations are not always good ,In fact they are mostly bad its rare if a mutation happens in a good way. If so its called an adaptation

Comment #3.3 by: scientificjargon on 20 Feb 2013, 07:22 GMT

It would not be referred to as an adaption. That is an entirely different thing, considering we are talking about mutations which can be good or bad. For example, sickle cell disease, it can be good as it can slow down horrible diseases such as malaria, yet it can clot arteries and cause stroke...


Comment #4 by: doomsayer on 07 Oct 2010, 03:49 UTC reply to this comment

down's syndrome is complicated its an irregular number of chromosome's which occurs during meiosis in the original sex cell's so it maybe that the parents have a mutation which increases the risk of this happening so they carry the gene but but aren't effected by it, so its a mutation that causes a mutation so to speak.
Natural selection would have dealt with this in the animal kingdom however humans have few natural predators so with modern medicine and with people willing to look after downs syndrome sufferers 24/7 natural selection doesn't get a chance. If there was a catastrophe tomorrow then believe me only the strongest would survive.


Comment #5 by: bob on 08 Nov 2010, 14:38 UTC reply to this comment

he looks like my grandma.

Comment #5.1 by: bubblysweetheart on 15 May 2011, 04:10 GMT

how does it happen
is it from dangerous amounts of radiation and is it a medical or military concern, what hapens if we loose control , what happens if they attack

Comment #5.2 by: bubblysweetheart on 15 May 2011, 04:10 GMT

thats not nice


Comment #6 by: somebody on 05 Aug 2011, 03:15 UTC reply to this comment

we share 99.99 percent of our genes with other humans, not 49.99 percent


Comment #7 by: Vadalon on 30 Jan 2012, 00:49 UTC reply to this comment

Blue-eyes and red-hair are also mutations, started from one person.


Comment #8 by: MikeJR on 05 Mar 2012, 15:56 UTC reply to this comment

The modern day word mutation should be redefined


Comment #9 by: Lee on 17 Apr 2012, 02:41 UTC reply to this comment

I've been wondering about mutations. My father had brown eyes and my mother blue eyes. Yet, I have eyes that consist of a brown ring inside a light green ring. The ring that edges the iris is dark blue. Also, I have learned some physical skills in a unique way. I learned how to ride a bicycle and how to swim by watching others and then doing what they were doing. I also know some self defense maneuvers the same way. I am also sensitive to light in my vision. I need to ofteh wear sunglasses outside. Even on brightly cloudy days and in winter. Can anyone tell me what's going on with these things?

Comment #9.1 by: Heterochromia iridum on 26 Apr 2012, 15:06 GMT

Heterochromia iridum refers to a difference in colouration of the eyes or skin ie one eye might be blue the other green i myself have blue eyes with an inner ring of green/gold


Comment #10 by: philosage on 27 Apr 2012, 02:29 UTC reply to this comment

actually, mammal norm is for adults to be lactose intolerant. 70% of humans still are. the mutation is lactose persistence.


Comment #11 by: Akinbami Sunday Olusesi on 14 May 2012, 06:23 UTC reply to this comment

Based on a part of the article that talks about "heredity", as a "beneficial mutation" in humans, isn't resemblance a perfect or partial match? If yes, I'm just thinking, mutation is probably applicable to bones.


Comment #12 by: ray on 08 Aug 2012, 21:17 UTC reply to this comment

astoundingly there are very few mutations and there are not even one beneficial one found or I am sure it would have been listed this begs the question how many mutations are required to accomplish the Human eye from its first rudimentary form to todays version. over how many generations and how many bad mutations would also have happened to the process before the eye worked Do any human fossil finds ever show any indication of a less complete eye socket or is there any evidence for a less complete eye? Hayzeed520@aol.com


Comment #13 by: Superhuman1 on 29 Sep 2012, 05:19 UTC reply to this comment

What about me, I do what I want and never work out, yet I have a physically fit body like a man who does. My whole family is obese but not my twin and myself. I get riddles at a higher intilectual level than anyone I have ever met. Like my father I am full of anger but with control. I see things before they happen. I can anticipate any situation as and succeed because of it. I have never lost. I also can do extraordinary things. Yet, my identical twin brother can do none of these. He works out daily, using extra superior supplements, yet I am still stronger, faster and more agile, and again I have. Ever lifted weights nor have I ever worked out. My parents call me a superhuman with abilities not of this world. Explain that. Oh, and I already know the answer. Not one person in this world has ever had it right.

Comment #13.1 by: Bustin' on 13 Oct 2012, 06:20 GMT

Okay someones been watching way too much x-men


Comment #14 by: Confused Christine on 14 Dec 2012, 22:10 UTC reply to this comment

What's with the picture of the guy from the Buffy the Vampire Slayer musical episode?


Comment #15 by: juanito on 27 Mar 2013, 14:55 UTC reply to this comment

Very, very interesting... nevertheless, I detected a slight machism in some numerals. I know it might be not your intention, nature is nature. Just don't show this to a feminist one. :)
Thank you, great work.

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