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Nano-Biotechnology


Stem Cells to Soon Cure the Lungs of Premature Babies

They worked amazing feats on animal models

By Tudor Vieru, Science Editor

28th of November 2009, 00:01 GMT

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Soon, premature babies could receive stem-cell treatment to improve the health of their lungs
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Stem cells are currently under large waves of self-righteous, moral criticism for nothing, when they could be saving lives. These precursor cells have proven their ability to cure or replace a large number of organs, including hearts, lungs, livers, skin, and so on. Just recently, it was shown that stem cells derived from the bone marrow could be used to synthesize treatments that could potentially save the lungs, and life, of babies born ahead of term. A new scientific study, detailing the mouse experiments, appears in the latest issue of the American Journal of Respiratory and Critical Care Medicine.

In charge of the investigation has been Dr. Bernard Thebaud, an expert that holds joint appointments, in the Royal Alexandra Hospital Stollery Children's Hospital Neonatal Intensive Care Unit, and at the University of Alberta Faculty of Medicine and Dentistry. The scientist found a way of bringing his two favored fields of research – helping small children born weeks ahead of term live, and his passion for stem cells – together, and created something tremendously useful. In their latest work, the expert and his team managed to show that exposing the lungs of prematurely born rats to stem cells was extremely beneficial, and healed the organs, ScienceDaily reports.

According to the test results, two weeks after stem cells were administered, the rats were able to run twice as faster, and also had higher survival rates than their peers in a control group, which were not given the stem-cell treatment. “The really exciting thing that we discovered was that stem cells are like little factories, pumping out healing factors. That healing liquid seems to boost the power of the healthy lung cells and helps them to repair the lungs,” Thebaud, who is also an Alberta Heritage Foundation for Medical Research clinical scholar, explains.

“The dilemma we face with these tiny babies is a serious one. When they are born too early, they simply cannot breathe on their own. To save the babies' lives, we put them on a ventilator and give them oxygen, leaving many of them with chronic lung disease. Before the next decade is out I want to put a stop to this devastating disease,” the expert says. “In a few short years, I anticipate we will be able to take these findings and begin clinical trials with premature babies,” University of California in San Francisco (UCSF) Professor of Pediatrics Dr. Roberta Ballard concludes.

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stem cells | lungs | rats | premature births | babies
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User opinions:


Comment #1 by: PaulineG on 28 Nov 2009, 10:18 GMT reply to this comment

"Stem cells are currently under large waves of self-righteous, moral criticism for nothing, when they could be saving lives."

Please do not conflate all stem cell therapies as though all are opposed on ethical grounds.

The stuff that is out there and working right now is not opposed because it does not involve the destruction of early human life.

We are currently subject to an endless stream of reports about potential treatments using embryonic stem cells. Yet no therapies as yet. Why?

For example, the human trials using embryonic stem cells announced with such fanfare in the 'States just after Obama's election have since been put on hold because of tumours developing in animal trials. Not a lot of publicity on that one!

Meanwhile, as well as the therapies already in place using 'adult' stem cells, the ethically uncontroversial induced pluripotent stem cell approach is showing huge promise and that's where the smart funds are now headed.


Comment #2 by: Kathy on 01 Dec 2009, 14:07 GMT reply to this comment

Vieru is either incredibly ignorant of the subject or a paid marketing rep. The stem cells usedin the experiment were adult stem cells, not embryonic (the article is published online at http://ajrccm.atsjournals.org/current.shtml) .

As everyone knows the "waves of self-righteous, moral criticism" is all aimed at EMBRYONIC stem cells, not adult stem cells. I am pro-choice, but the pushing of embryonic stem cells is all about money. Adult stem cells (especially one's own) threaten enormous pharmaceutical profits while embryonic cells spell layers and layers of patents, royalties and $$$ for pharmaceuticals.

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