Spider-Man 3 is a video game based on the Spider-Man 3 film. It was released May 4, 2007. The scenario draws from the film, Spider-Man comics and the Marvel Universe. The game features
nine villains on the PS3, Xbox 360, and PC, five villains on the GBA and DS, and eight on the Wii, PlayStation Portable and PlayStation 2, including the movie's primary villains Venom, New Goblin, and Sandman.
Many gameplay elements have been added and revised for this title in the series: Manhattan is much bigger than in Spider-Man 2, and the game features over 20 miles of sewers and subways, Spider-Man has a brand new combat system that was worked from the ground up and includes more aerial moves and web attacks and many more.
(Wikipedia)
GAMEPLAY HINTS
Defeating Michael Morbius
When you are trying to open the boarded up windows, if you are far away from him he will do a long jump towards you. Then it takes him a few seconds to recover to attack. Before he jumps, do not stand in the yellow circles. Instead, stand next to the wall opposite the windows. He will now jump to there, recover, etc. While he is recovering, pull down the boards. When he jumps into the light, attack him. Keep doing this until his and his wife's life runs out to complete the level.
Defeating Shriek
In your final encounter with Shriek, she temporarily takes away your Black suit, and figures from your imagination attack you (your loved ones). You can kill them with one hit, but it is pointless. Wait until the Black suit recharges, then switch over, revealing your true enemies. Attack Shriek until she changes you back to the old Spider-Man. Repeat the previous steps and she will collapse.
Defeating Michael Morbius and Shriek
Wait until Michael is about to rush you, then open the window. He will be temporarily weakened. Beat him up. Shriek will heal him, losing some of her health. Repeat this until he dies, and she flees the scene.
Defeating Venom
Before this battle, go to the upgrade menu and make sure you have the melee attack volley. Then, fight. Depending on your health level, you may or may not want to use the power up. At the moment, you can easily jump over Venom, confuse him, and chip away at his health. Keep doing this until his black suit begins to "glow". Now when you jump over him he will run away. This is a good opportunity to use your new attack and chip at him, occasionally giving some hits. Keep hitting him until his "glow" gets bigger and eventually Harry will tell you to knock Venom into the air. He'll fall back to the ground same as before, easily confused. Repeat this cycle until his health is really low and you can finish him off.
Easy gang eradication
Immediately after you defeat The Sandman for the first time in the "Mary Jane's Favorite Band" mission and before you "Meet Mary Jane At The Restaurant", you cannot take off the Black suit. During this time period, which does not end until you start the next mission, you can wear the Black suit without any damage being done to you. Use this time to clear the city of all gang activity. This may take awhile, but it is easier with the Black suit.
Random gang
When you go to a crime area controlled by the police, you will be assigned a task involving a random gang. On completion of the tasks the effectiveness of the police will be increased (as seen by the rings around the police symbol on the map). The more rings you have, the harder it is for gangs to take control of police-controlled areas and the more likely it is for the police to take over gang controlled areas.
Construction site
After you have completed the Final Showdown mission, swing somewhere far then go on the map and look for the Financial District. Go there. Go to the left until you see a glass building. That is the construction site after it was broken Note: You will see the little square that you was fighting in with Venom and Sandman.