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August 17th, 2007, 18:06 GMT · By Stefan Anitei

Meth Induces Parkinson's Disease

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When taking meth, a burst of dopamine makes you euphoric, extremely dynamic, full of energy and you do not even need to eat. But after that, blood pressure increases and there is a risk of stroke and severe heart issues, besides hallucinations.

Methamphetamine (also known as meth, crank, crystal and speed), a powerfully addictive drug, has been used by more than
12 million people in the US. Celebrities like Fergie from the Black Eyed Peas have had a long publicized battle with the drug.

It is a psychostimulant and sympathomimetic chemical, prescribed for severe cases of attention-deficit hyperactivity disorder (narcolepsy) as Desoxyn. It can be taken orally, injected, snorted or smoked. Most users are 18 to 34 years old. It is known that in just one year, the drug users can lose all their teeth (the "meth mouth").

Users become obsessed, doing repetitive tasks like cleaning, hand-washing, or assembling and disassembling objects. Withdrawal induces excessive sleeping, eating and depression-like symptoms, besides anxiety and drug-craving.

But the drug makes more than 'stealing' your teeth and personality: a new research shows that young adults consuming methamphetamine are more likely to experience age-related brain diseases/disorders long after they interrupt the consume. Thus, even if the drug's current use may not produce immediate results, the issues will install as the person grows old.

The methamphetamine administered for a long time on the mice appeared to partially reduce the glial derived neurotrophic factor (GDNF), a protein that protects and resinthesizes dopamine, which is a crucial brain neurotransmitter connected to motor control, and whose lack is a main factor causing Parkinson's disease.

"These studies speak directly to the possibility of long-term public health consequences resulting from the current epidemic of methamphetamine abuse among young adults. Methamphetamine intoxication in any young adult may have deleterious consequences later in life, although they may not be apparent until many decades after the exposure," said Jacqueline McGinty, researcher at the Medical University of South Carolina.
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READER COMMENTS:


Comment #1 by: user1 on 12 Jul 2009, 21:16 UTC reply to this comment

Nothing in this document provides any validity for claiming that methamphetamine use causes Parkinson's, nor has any blinded study demonstrated that methamphetamine causes Parkinson's. This is not to say that methamphetamine doesn't cause alarming brain problems, but it does no good to exaggerate our outright fabricate these things.

Comment #1.1 by: austin on 27 Dec 2009, 04:27 GMT

AMEN! i get tired of these studies that pretty much use "scare" tactics. If were going to do something about this drug then it needs to be looked at honestly. I did methamphetamine a few times over 10 years ago and show no signs of any harm done. Now thats not to say that meth cant be a very destructing drug but what do you think these kids are going to think when they find out that every thing your telling them is some exagerated or undocumented BS.


Comment #2 by: Dawn on 23 Dec 2009, 14:21 UTC reply to this comment

I believe Meth does contribute to developing Parkinson's disease because the simple fact is....Meth releases excess dopamine.....and after a long period of time your body gains a tolerance to the dopamine so I can see how it is related....My father was just recently diagnosed with Parkinson's Disease and he is a long time Meth user and I think it contributed directly to his developing Parkinson's.

Comment #2.1 by: M.ariya on 01 Jan 2010, 08:02 GMT

Very sad but true that whatever we do to go up must come down etc and so forth. There is no safe way to use addictive substances. In spite of the fact that after I stopped all use of drugs and alcohol 28 years ago, became an athlete and have taken excellent care of my body and brain I have been diagnosed with Parkinsons Disease due to a 5 year crystal methamphetamine run. I am sad to realize that I am somewhat responsible for this debilitating condition of slow and progressive degeneration of what once was a vibrant surfer and beautiful intelligent woman.


Comment #3 by: M.ariya on 01 Jan 2010, 07:44 UTC reply to this comment

I agree with this hypothesis. As a crank user from age 28 - 33 I wreacked havoc on my brain. Since stopping all use I have had difficulty focusing and being tangential at times. I took really good care of myself over the past 28 years of being sober and drug free. Was very athletic by running daily until I began surfing and diving. 2 years ago I was diagnosed with Parkinsons Disease. I am sure that the abuse and addiction to crystal methamphetamine has been responsible for causing my brain to be dopamine deficient.


Comment #4 by: anonymous on 19 Mar 2011, 01:29 UTC reply to this comment

lol @ all the meth users defending illicit drugs


Comment #5 by: mson on 01 Jan 2012, 16:57 UTC reply to this comment

My father used meth for 25 years and now has terrible parkinsons and many other health problems and can no longer even function without meth

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